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UNIVERSITY STUDIES

Case Studies

Aminophylline works wonders, and these are some case studies that prove it.

Topical fat reduction from the waist.

Diabetes Obes Metab. 2007 May;9(3):300-3.

Caruso MK, Pekarovic S, Raum WJ, Greenway F.

Source

Louisiana State University Division of Human Ecology, Baton Rouge, LA, USA.


Objective -
Reduction in the thighs, has been proven using Aminophylline, by reducing the lypolytic threshold. This study is to prove that applying the cream to the waist, it can reduce cellulite levels on other areas of the body.

Methods & Procedures for Research -
50 men, aged 21 to 65, with a BMI over 27, and waist to hip ratio of greater than 1:1, used .5% Aminophylline cream twice daily. All followed a 1200 calorie diet, and had to walk or do light exercise daily; at the end of 12 weeks, theopylline levels were drawn, the waist and BMI were measured as well.

Results -
At the 12 week mark, the BMI was not different, a reduction in the waist was 11 +/ 1 - , for the Aminophylline group, versus 5 +/ .6 - , in the non user group. Women lost more waist girth, and no adverse effects were detected by the group using the Aminophylline cream.

PMID: 17391155 [Pubmed - indexed for MEDLINE]

--Louisiana State University Division of Human Ecology, from PubMed.gov, 2007 May 9th.

Topical fat reduction.

Obes Res. 1995 Nov;3 Suppl 4:561S-568S.

Greenway FL, Bray GA, Heber D.

Source

Abstract -
Increased alpha 2, makes cellulite on women's thighs harder to mobilize; receptor stimulation can stimulate lypolisis. Many women desire smaller thighs; for this reason, a double blinded test study was conducted, to determine if localized fat loss and reduction was possible, using different test methods to determine the success or failure of localized fat loss.

1st trial -
Isoproternol injections were given to 5 overweight women to the thigh, three times weekly for a period of four weeks; they were also instructed to walk and diet.

2nd trial -
5 overweight women used an ointment containing forskolin, Aminophylline, and yohimbine, applied five times a week to the thighs, for four weeks. Diet and walking were also suggested in the group.

3rd trial -
18 women were split into 3 groups, and the 2nd trial, along with placebo groups were set up, using separate ointments, to determine the success of the second trial group.

4th trial -
30 overweight women were given a 10% Aminophylline ointment, which was applied 5 times weekly, for a period of 6 weeks. They were also conducted to walk and diet; a chemistry panel, patch testing, and theophylline levels, were all conducted on these women.

5th trial -
12 women from the 4th trial, did the study with 2% Aminophylline, and were conducted to forgo doing the diet and walking each day.

6th trial -
The 5th trial was repeated, but only using a .2% Aminophylline ointment.

The end result of the trials conducted, was that every group, except the yohimbine group, lost a significant amount of girth around the thigh areas where the topical solutions were applied for targeted weight loss. No toxicity levels were shown, through the chemistry panels that were conducted during the studies either. Theophylline was not detected through the studies and tests that were conducted with the women using the Aminophylline cream; and, patch testing that was conducted on the women, also showed as a negative result through the tests that were run.


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